masters level dissertation in chemistry
very complicated task
Aqueous two-phase systems based on ethyl lactate is an innovative technique to separate biomolecules that combines the advantages of liquid-liquid extraction and hydrophilic bio renewable solvent. Due to the complexity of these systems, rigorous models based on
theory are not available. Therefore, the empirical equation given by Merchuk is usually used to
describe bimodal curves. However, Merchuk’s equations provide a poor extrapolation ability.
Therefore, the aim of this work is the analysis of other equations, comparing the models
reported in the literature and proposing alternative equations to improve accuracy or to reduce
the mathematical complexity. The research objectives of this project are:
i) To compile a database containing experimental data of solubility of nine aqueous
biphasic systems based on ethyl lactate;
ii) To select statistical criteria to be used for the selection of models;
iii) To fit various empirical models to experimental data;
iv) To analyze and compare the effectiveness of empirical models, allowing discussion of
the advantages and disadvantages of each equation.
MS Excel will be used as calculation tools. For more information on Chemistry Dissertation see this: https://en.wikipedia.org/wiki/Thesis
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